
The Last Days of Ptolemy Grey
2022 · TV series · 1 season
Created by Walter Mosley
Suddenly left without his trusted caretaker, Ptolemy Grey is assigned to the care of orphaned teenager Robyn. When they learn about a treatment that will restore Ptolemy’s dementia-addled memories, it begins a journey toward shocking truths.
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> Within hours of the first injection, the animal brains showed a nearly 45 percent reduction in clumps of amyloid-beta plaques, a hallmark of Alzheimer's disease.
> The mice had previously shown signs of cognitive decline, but after all three doses, the animals performed on par with their healthy peers in spatial learning and memory tasks. The benefits lasted at least six months.
1. This is great news… for mice with Alzheimer’s that don’t mind treatments every 6 months.
2. It’s crazy to think about something like this actually curing Alzheimer’s in humans, even if for just 6 months. Even more so if repeated doses have the same effects.
3. As with all of these studies, mice != humans, but it’s nice to have hope.
Side note: the temporary part of #2 makes me think about The Last Days of Ptolemy Grey [1]. It’s hard to fathom having a relative “come back” like that for a short time. Or even permanently.
[1] https://www.imdb.com/title/tt13820498